3. Common human drugs that are harmful to pets. Several commonly used human medicines can put dogs at serious risk. These include nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, and painkillers such as acetaminophen (Tylenol). Pets can also become poisoned by other drugs, including antidepressants, antihistamines, and sleeping pills. It is important to be aware of these risks and not give your pet human medicines to self-medicate.